Epithelial Cadherin, Amino-Terminal Domain

Epithelial or E-cadherin is a transmembrane protein. It provides epithelial cells with calcium-dependent cell-adhesion. The amino-terminal domain of E-cadherin matches the first out of five extracellular repeats. This domain is roughly 100 amino acid residues long. It consists of 7 beta strands (gold) and a single 310 alpha helix (purple). The secondary structure of the amino-terminal domain is characterized as a beta-barrel fold, similar to that of the immunoglobin fold.


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