RBP-MS RNA-binding domain, homology model

The human RNA-binding protein with multiple splice sites (RBP-MS) has been constructed using homology modeling. The homology model depicts the RNA-binding domain of RBP-MS. The template protein which RBP-MS was modeled after is snRNP (small nuclear RiboNuclear Protein) U1A, specifically the N terminal RNA-binding region of snRNP U1A. The RNA-binding domain of RBP-MS shares about 22% sequence identity with snRNP U1A.
The RNA-binding domain of RBP-MS is 97 amino acid residues long, and it is an alpha-beta protein. It consists of 3 alpha-helices (purple) and 4 beta-sheets (seagreen). The function of the RBP-MS gene is not yet known.


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