Tendamistat

Tendamistat is a protein which specifically inhibits mammalian alpha-amylases. It forms a strong stoichiometric 1:1 complex with the enzyme alpha-amylase. This protein however, has no effect on the alpha-amylases of plants or microbes.
Tendamistat is 74 amino acid residues long. The only secondary structure found in the protein are six beta sheets shown here in blue. The protein also contains two disulfide bridges; Cys11-Cys27 and Cys45-Cys73 which are shown in pink.


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