NESG Gene Fusions

Partially Unfolded Proteins

Name Solved Method N-Function C-Function N-Gene ID C-Gene ID Fusion Gene ID Query Genome (from genome) Fusion Genome (in genome) Fusion Score* Separation Index** Image
LmR11 N/A1 similar to phosphoribosyl-AMP cyclohydrolase similar to phosphorybosil-AMP-cyclohydrolase 16799646 16799645 20806542 Listeria innocua Thermoanaerobacter tengcongensis strain MB4T, complete genome 0.82 1.0 view
CvR16 N/A1 orf, hypothetical protein GTP cyclohydrolase II 16128766 16129238 28899855 Escherichia coli K12 lactis Vibrio parahaemolyticus RIMD 2210633 chromosome II, complete sequence 0.81 0.99 view
MhR41 N/A1 hypothetical protein, similar to DNA helicase Clumping factor B 15925797 15928216 20088899 Staphylococcus aureus N315 Methanosarcina acetivorans str. C2A, complete genome 0.51 0.43 view
BhR21 N/A1 transcriptional regulator BH1328~unknown conserved protein 15613464 15613891 11497325 Bacillus halodurans Borrelia burgdorferi plasmid cp32-9, complete sequence 0.45 0.36 view
SR128 N/A1 similar to unknown protein similar to B. subtilis comG operon protein 1 16800241 16800452 15603881 Listeria innocua Rickettsia prowazekii strain Madrid E, complete genome 0.39 0.10 view

1N/A designates that the structure for this protein has not yet been solved.

*The fusion index is the fraction of residues of the concatenated two putative fusion genes that are chemically related to the residues of the target gene when placed in a pair-wise alignment: it is the number of dots, columns, and stars in the T-COFFEE alignment divided by the size of the length of the concatenated genes.

**The separation index is a measure for the mix between the domains of the two putative fusion genes when placed in a triple alignment to the target gene. Separation indices greater than .6 indicate a true gene fusion event