NESG Gene Fusions

Largely Unfolded Proteins

Name	Solved Method	N-Function	C-Function	N-Gene ID	C-Gene ID	Fusion Gene ID	Query Genome (from genome)	Fusion Genome (in genome)	Fusion Score*	Separation Index**	Image
KR12	N/A¹	pantothenate metabolism flavoprotein	flavoprotein	15672554	15672555	23097455	Lactococcus lactis	Oceanobacillus iheyensis, complete genome	0.71	1.0	view
PsR51	N/A¹	yersiniabactin biosynthetic protein	putative thioesterase	16122158	16121086	13488050	Yersinia pestis	Mesorhizobium loti plasmid pMLa, complete sequence	0.35	0.67	view
XR5	N/A¹	hypothetical protein	50S ribosomal protein L40	14601115	14600459	13507739	Aeropyrum pernix	Mycoplasma pneumoniae, complete genome	0.50	0.33	view
SmR3	N/A¹	lipopolysaccharide biosynthesis glycosyltransferase	ribosomal protein L28	15640254	15640248	14518450	Vibrio cholerae	Pyrococcus abyssi, complete genome	0.39	0.32	view
SpR5	N/A¹	lipopolysaccharide biosynthesis glycosyltransferase	ribosomal protein L28	15640254	15640248	14518450	Vibrio cholerae	Pyrococcus abyssi, complete genome	0.39	0.32	view
HR2078	N/A¹	BH3997~unknown conserved protein	heat-shock protein	15616559	15613908	14589963	Bacillus halodurans	Pyrococcus horikoshii, complete genome	0.27	0.20	view

¹N/A designates that the structures for these proteins have not yet been solved.

*The fusion index is the fraction of residues of the concatenated two putative fusion genes that are chemically related to the residues of the target gene when placed in a pair-wise alignment: it is the number of dots, columns, and stars in the T-COFFEE alignment divided by the size of the length of the concatenated genes.

**The separation index is a measure for the mix between the domains of the two putative fusion genes when placed in a triple alignment to the target gene. Separation indices greater than .6 indicate a true gene fusion event