The CABM Structural Bioinformatics Laboratory carries out structure and function studies of genomically-defined protein targets. The lab uses both NMR and X-ray crystallography, along with computational methods, to address questions emerging from genomic and functional genomic analyses. The lab also develops software to automate structure determination by NMR methods. It is one of the principal nodes of the United States Protein Structure Initiative.
- Structure of RNA-binding Domain of the NS1 Protein from Avian Influenza Virus: a Potential Target for Antiviral Drug Development.
- Nature Methods: Together at last: crystallography and NMR
IN THE NEWS: Professor Gaetano Montelione and Davide Comoletti, Assistant Professor at the Child Health Institute of New Jersey have been awarded one of the National Science Foundation (NSF) Early Concept Grant for Exploratory Research (EAGER). This funding mechanism is part of President Obama's BRAIN Initiative, aimed at generating transformative insights into understanding the connectivity of the brain. The project is entitled "The Molecular Interactome of Synaptogenisis"