The CABM Structural Bioinformatics Laboratory carries out structure and function studies of genomically-defined protein targets. The lab uses both NMR and X-ray crystallography, along with computational methods, to address questions emerging from genomic and functional genomic analyses. The lab also develops software to automate structure determination by NMR methods.
- Nature Methods: Solving Large Protein Structures By NMR. Two papers address this challenge by presenting hybrid methods that couple sparse NMR information with alternative structural information in order to solve protein structures. Read the full article here: Nature Methods
- Congratulations to Christopher Kim on winning a Jerome and Lorraine Aresty
Undergraduate Research Fellow Award.
Chris is working in the Montelione lab in collaboration with Shridar Ganesan, CINJ, researching the suppression of oncogenic TRIM fusion proteins by arsenic.